(Tao L, 2023; 522,273 prescriptions of PrEP were analyzed between January 2019 and February 2023, selected from IQVIA® LAAD. Observational study compared delays of PrEP dispensation from day 0, when PrEP was dispensed.2)
IQVIA LAAD=IMS Health, Quintiles, and VIA Longitudinal Access and Adjudication Data.
Screen for HIV1
A negative HIV test is required. Some PrEP options also require HBV screening and confirmation of CrCl levels.
Counsel individuals3
How to take their PrEP medication for HIV prevention and safer sex practices to prevent STIs.
Regularly screen for STIs3
Some PrEP options also require continued renal function monitoring.
Talk about PrEP as soon as possible with the individuals in your practice who may need or want it.
CrCl=creatinine clearance; HBV=hepatitis B virus; STI=sexually transmitted infection.
CrCl=creatinine clearance; HBV=hepatitis B virus; STI=sexually transmitted infection.
References:
1. Centers for Disease Control and Prevention. HIV Nexus: CDC resources for clinicians. Updated August 20, 2024. Accessed September 4, 2024. https://www.cdc.gov/hivnexus/hcp/prep/index.html
2. Tao L, Yang J, Zachry W, Gruber J, Mezzio D. The real-world impact of pre-exposure prophylaxis (PrEP) prescription uptake and dispensing status on HIV infection risk in the US. Poster presented at: IDWeek 2023; October 11-15, 2023; Boston, MA. Poster 1557.
3. Centers for Disease Control and Prevention. US Public Health Service: Preexposure prophylaxis for the prevention of HIV infection in the United States—2021 Update: a clinical practice guideline. Accessed September 12, 2024. https://www.cdc.gov/hiv/pdf/risk/prep/cdc-hiv-prep-guidelines-2021.pdf
4. Data on file. Gilead Sciences, Inc.
5. Nicoletti B; HIV Medicine Association. Billing Coding Guide for HIV Prevention. National Alliance of State and Territorial AIDS Directors (NASTAD). Published April 2016. Accessed September 12, 2024. https://nastad.org/sites/default/files/2021-12/PDF_BillingCodingGuide_v5.pdf
6. Recommendations for HIV prevention with adults and adolescents with HIV in the United States, 2014. Centers for Disease Control and Prevention. Published December 11, 2014. Accessed September 15, 2024. https://stacks.cdc.gov/view/cdc/44064